Driving in Mexico is a mixture of Need for Speed & demolition derby. For the most part, being aware of a few simple rules will greatly help your driving experience.
1. Beware of "Topes" - the Mexican speed bump, and it's relative the "reverse tope" - a Mexican trench style speed bump. If you value your suspension, you will want to keep focused on the road and slow down for topes.
2. Turn right to turn left! If you are driving on the 200 and want to turn left, you will first need to get on the lateral (right) and at the light stay on the left till you get a green left turn light. If you wish to keep driving straight on the lateral, at the light, stay on your right side.
3. Turn signals seem to be optional on Mexican cars and trucks. If you are on a twisty highway and the truck in front of you puts their left turn signal, it's an indication that the coast is clear for you to pass them. Of course, if you put your turn signal to pass, you are telling the person behind you to pass so beware!
4. Keep your distance, working brake lights are a luxury in Mexico!
5. Drive only during the day if possible. Topes, livestock and po holes are all things that could disrupt your trip.
6. Many roads have no "STOP" signs, so slow down and if in doubt, be polite and give the other driver the right of way.
Make sure you have Mexican car insurance, as US/Canadian insurance is not valid in Mexico. You should also ensure that your insurances includes a claims adjuster and an attorney. If you are in a car accident, you might be taken to jail till the authorities can establish fault, especially if there are injuries.
TIP: If a vehicle hits you, do your best to get a licence plate number. If a local hits you and they don't have the proper paperwork, they will be put in jail till they can produce bail. They then have to settle with you on an amount. Don't sign anything under pressure and unless you clearly can understand what is being asked of you.